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CD4 — CXCL12

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: CXCL12 — CD4 (in vitro) Mbemba et al., Virology 1999*
• IRef Ophid Interaction: CXCL12 — CD4 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
• IRef Ophid Interaction: CXCL12 — CD4 (aggregation, confirmational text mining) Mbemba et al., Virology 1999*

Text-mined interactions from Literome

Megiovanni et al., Eur Cytokine Netw 2004 : We then examined whether ligation of CD4 , CCR5 andor CXCR4, the receptor and coreceptors of human immunodeficiency virus envelope gp120, respectively, affected DC activation or maturation, neither a monoclonal antibody to the gp120 binding site on CD4 nor CCL5 nor CXCL12 , the natural ligands of CCR5 and CXCR4, respectively, nor gp120 altered the DC activation and maturation processes
Thakkar et al., Antimicrob Agents Chemother 2009 (HIV Infections) : NB325 also inhibited chemotaxis of CD4 ( + ) T lymphocytes induced by the CXCR4 ligand CXCL12