Hong et al., Life Sci 2001
:
Activated PI 3-kinase ( H9c2-p110* ) and pretreatment of cells with IGF-1 down-regulated Bax protein levels compared to control cells
Cheng et al., Nat Med 2004
(Breast Neoplasms...) :
The inhibition of apoptosis was associated with a decrease in expression of the proapoptotic molecules, BAK and BAX , and activation of the antiapoptotic phosphatidylinositol 3 kinase (PI3K) and AKT pathway, providing potential mechanisms for the effects of RAB25 on tumor aggressiveness