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CKS1BP7 — PCNA
Text-mined interactions from Literome
Reynard et al., Mol Cell Biol 2000
:
We show here that
Cks1 is
required for the protein kinase activity of budding yeast G ( 1 )
cyclin-CDK complexes ... The
role of
Cks1 in promoting G ( 1 )
cyclin-CDK protein kinase activity both in vitro and in vivo provides a simple molecular rationale for the essential role of CKS1 in progression through G ( 1 ) phase in budding yeast
Sitry et al., J Biol Chem 2002
:
Previous studies have shown that the
cyclin dependent kinase (Cdk) inhibitor p27 ( Kip1 ) is targeted for degradation by an SCF ( Skp2 ) ubiquitin ligase complex and that this process
requires Cks1 , a member of the highly conserved Suc1/Cks family of cell cycle regulatory proteins