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MAPK1 — NOS3

Text-mined interactions from Literome

Nandan et al., Infect Immun 1999 : Activation of phosphotyrosine phosphatase activity attenuates mitogen activated protein kinase signaling and inhibits c-FOS and nitric oxide synthase expression in macrophages infected with Leishmania donovani
Maeda et al., J Pharmacol Exp Ther 2000 : The endothelial NOS gene transfer did not affect endothelin-1 induced increase in [ Ca ( 2+ ) ] ( i ) of type A receptor transfected cells, but markedly inhibited mitogen activated protein kinase and c-fos promoter activities
Shaul et al., Semin Perinatol 2000 : The inhibition of calcium influx, or tyrosine kinases or mitogen activated protein ( MAP ) kinase prevents eNOS stimulation by estrogen, and estrogen causes rapid ER-dependent activation of MAP kinase
Xu et al., Life Sci 2000 (Glioma...) : P38 MAPK , but not p42/p44 MAPK mediated inducible nitric oxide synthase expression in C6 glioma cells
Fabrizi et al., J Biol Chem 2001 : The stimulation of inducible nitric-oxide synthase by the prion protein fragment 106 -- 126 in human microglia is tumor necrosis factor-alpha dependent and involves p38 mitogen activated protein kinase
Llansola et al., Brain Res 2002 : Activation of N-methyl-D-aspartate ( NMDA ) receptors leads to increased phosphorylation of the microtubule associated protein MAP-2 by a mechanism that involves activation of nitric oxide synthase and nitric oxide induced activation of mitogen activated protein kinase ( MAP-kinase )
Simkhovich et al., Cardiovasc Pathol 2003 (Myocardial Ischemia) : Protective genes included mitogen activated protein kinase activated protein kinase 3 ( MAPKAPK 3 ), heat shock proteins 70, 27, 22, B-crystalline, vascular endothelial growth factor, inducible nitric oxide synthase and plasminogen activator inhibitors 1 and 2
Wang et al., J Pharmacol Exp Ther 2003 : Up-regulation of endothelial nitric-oxide synthase by endothelium derived hyperpolarizing factor involves mitogen activated protein kinase and protein kinase C signaling pathways
Platten et al., Biochem Pharmacol 2003 : Involvement of protein kinase Cdelta and extracellular signal regulated kinase-2 in the suppression of microglial inducible nitric oxide synthase expression by N- [ 3,4-dimethoxycinnamoyl ] -anthranilic acid ( tranilast )
Kitamura et al., Diabetologia 2003 : Proinsulin C-peptide increases nitric oxide production by enhancing mitogen activated protein-kinase dependent transcription of endothelial nitric oxide synthase in aortic endothelial cells of Wistar rats
Wahren et al., Exp Diabesity Res 2004 : Binding of C-peptide results in activation of Ca2+ and MAPK dependent pathways and stimulation of Na+, K ( + ) -ATPase and eNOS activities
Anter et al., J Biol Chem 2004 : Activation of endothelial nitric-oxide synthase by the p38 MAPK in response to black tea polyphenols
Wang et al., Atherosclerosis 2006 : Inhibitors of PPARalpha, PI3 kinase and MAPK , respectively, markedly attenuate bezafibrate induced upregulation of eNOS
Krolikowski et al., Can J Anaesth 2006 (Myocardial Reperfusion Injury) : We tested the hypothesis Erk1/2 , p70s6K, and eNOS mediate isoflurane induced postconditioning in rabbit myocardium in vivo
Donnini et al., J Pharmacol Exp Ther 2006 : Consistently, in cultured coronary endothelial cells ( CVECs ), ACEI up-regulated endothelial NOS (eNOS) and FGF-2 and induced mitogen activated protein kinase extracellular signal regulated kinase 1/2 activation
Simoncini et al., Fertil Steril 2006 : Measure of NO release, endothelial nitric oxide synthase (eNOS) activity and expression, and activation of ERK 1/2 and Akt
Jiang et al., Prostaglandins Other Lipid Mediat 2007 (MAP Kinase Signaling System) : However, inhibitors of protein kinase B ( Akt ), mitogen activated protein kinase ( MAPK ) and MAPK kinase could block phosphorylation of eNOS at both sites
Grossini et al., Endocrinology 2008 : In porcine aortic endothelial cells, genistein induced the phosphorylation of endothelial nitric oxide synthase and NO production through ERK 1/2 , Akt, and p38 MAPK pathways, which was prevented by the concomitant treatment by butoxamine and fulvestrant
Johnson et al., Biol Reprod 2008 : The protection offered by the caspase 2 inhibitor occurred upstream of mitochondria, involving suppression of mitogen activated protein kinase ( MAPK) 14 activation and inducible nitric oxide synthase ( NOS2 ) induction and, in turn, suppression of cytochrome c-mediated death pathway
Grummer et al., Biochem J 2009 : Although VEGF ( 165 ) also activates ERK ( extracellular-signal regulated kinase ) -1/2, this is not necessary for eNOS activation since U0126 blocks ERK-1/2 phosphorylation, but not eNOS activation, and the VEGFR-2 kinase inhibitor inhibits eNOS activation, but not ERK-1/2 phosphorylation
Tokudome et al., Arterioscler Thromb Vasc Biol 2009 (Ischemia) : In cultured human endothelial cells, ANP treatment significantly stimulated mRNA expressions of vascular endothelial growth factor and endothelial nitric oxide synthase via Erk1/2 dependent mechanism
Chen et al., Mol Biol Rep 2010 (Inflammation...) : However, the anti-inflammation effects of eNOS in infarcted myocardium and the role of MAPK signaling in eNOS/NO mediated cardiac remodeling have not yet been elucidated ... Phosphorylation of MAPK after MI were also dramatically reduced by eNOS gene transfer
Ralay Ranaivo et al., Brain Res 2010 (MAP Kinase Signaling System) : Albumin activated ERK1/2, p38 MAPK and JNK signaling pathways in astrocytes, and induced the production of interleukin (IL)-1beta, inducible nitric oxide (NO) synthase , the NO metabolite nitrite, and the chemokine CX3CL1 while reducing the level of S100B
Lee et al., Am J Physiol Cell Physiol 2010 (Anoxia) : Hypoxia induced endothelial nitric oxide synthase (eNOS) phosphorylation was regulated by p38 MAPK and SAPK/JNK activation
Erdogdu et al., J Mol Endocrinol 2013 : Palmitate induced apoptosis stimulated cells to release NO and ROS, concomitant with upregulation of eNOS , which required activation of p38 MAPK and JNK
Nishiya et al., FEBS Lett 1997 (Glioma) : Activation of Stat1 and subsequent transcription of inducible nitric oxide synthase gene in C6 glioma cells is independent of interferon-gamma induced MAPK activation that is mediated by p21ras