Gene interactions and pathways from curated databases and text-mining

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ADM — NOS2

Text-mined interactions from Literome

Gupta et al., Shock 2007 (Hypotension) : Overall, we demonstrate that APC blocks the induction of ADM , likely mediated by IFN-gamma and iNOS , and suggests a mechanism that may account for ameliorating LPS induced hypotension
Li et al., Zhongguo Ying Yong Sheng Li Xue Za Zhi 2005 : L-NAME had no effect on iNOS protein, ADM promoted iNOS expression ( P < 0.01 ) ... ( 2 ) Hypoxia induces the expression of iNOS, ADM can increase expression of iNOS , ADM and INOS plays a role of protection in HPH pathogenesis
Yoshimoto et al., Br J Pharmacol 1998 : 8. These results suggest that in the rat aorta, adrenomedullin and alpha-CGRP increase the endothelial [ Ca2+ ] i, activate nitric oxide synthase and release nitric oxide, without a direct inhibitory action on smooth muscle