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BCR — PKD1
Text-mined interactions from Literome
Haxhinasto et al., J Immunol 2003
:
In this study, we show that genetic or pharmacologic inhibition of
BCR mediated
PKD activation in B lymphocytes abrogated the synergy between the CD40 and the BCR, as measured by activation of Ig and cytokine secretion
Vigorito et al., Cell Signal 2006
:
We found that
PKD activation upon BCR engagement or coligation of the
BCR with CD19 is entirely dependent on PI3K and PLCgamma but differ in the requirement for Vav proteins
Pracht et al., Cell Signal 2007
:
Finally, splenocytes from PKC-delta-deficient mice are found to exert reduced phosphorylation of
PKD ( a.k.a. PKC-mu ) in
response to
BCR engagement, suggesting the early, membrane-proximal activation of an attenuating kinase complex including PKC-delta and PKD