Kirovski et al., Am J Pathol 2011
(Carcinoma, Hepatocellular...) :
MTA induced matrix metalloproteinase ( MMP ) and interleukin-8 transcription in HCC cells in vitro, accompanied by enhanced proliferation and activation of the transcription factor NF?B
Shimizu-Hirota et al., Genes Dev 2012
:
In turn, MT1-MMP dependent PI3Kd activation regulates the immunoregulatory Mi-2/NuRD nucleosome remodeling complex that is responsible for controlling macrophage immune response