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AHR — IL10

Text-mined interactions from Literome

Wilson et al., J Clin Invest 2007 (Asthma...) : IL-10 also has paradoxical effects on Th2 associated pathology, with IL-10 deficiency resulting in increased Th2-driven inflammation but also reduced airway hyperreactivity (AHR) , mucus hypersecretion, and fibrosis
Apetoh et al., Nat Immunol 2010 : After T cell activation under Tr1 skewing conditions, the AhR bound to c-Maf and promoted transactivation of the Il10 and Il21 promoters, which resulted in the generation of Tr1 cells and the amelioration of experimental autoimmune encephalomyelitis