◀ Back to PI3

ERBB2 — PI3

Text-mined interactions from Literome

Ram et al., J Cell Physiol 2000 (Breast Neoplasms) : Phosphatidylinositol 3-kinase (PI3K) is activated by p185(erbB-2) /erbB-3 heterodimers in cells stimulated by HRG, and PI3K is constitutively activated by p185(erbB-2) /erbB-3 in breast carcinoma cells that overexpress c-erbB-2
Hellyer et al., J Biol Chem 2001 : Recruitment of PI 3-kinase to ErbB3 was required for both activities, and it appeared that ErbB2 activation alone was not sufficient to activate PI 3-kinase signaling in these cells
Choi et al., Cancer Lett 2006 (Breast Neoplasms) : Blocking the ERK, p38 kinase or PI3-kinase activity had no effect on the resveratrol-inducible transactivation of the erbB2 gene and the ErbB2 expression level
Madson et al., Am J Pathol 2009 (Cell Transformation, Neoplastic...) : Since Akt phosphorylates Chk1-Ser ( 280 ), the effect of Erbb2 on phosphatidyl inositol-3-kinase (PI3K)/Akt signaling during UV-induced cell cycle arrest was determined