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IL12A — NR3C2

Text-mined interactions from Literome

Nishioka et al., J Leukoc Biol 2003 (Lymphoma, T-Cell...) : We examined the mechanisms involved in interleukin (IL)-12 mediated suppression of cellular immunity in mice using allogeneic mixed leukocyte reaction (MLR) stimulated by dendritic cells (DCs) in vitro and compared the effect of IL-12 on MLR in mice and humans ... Although IL-12 stimulated human MLR , the addition of IL-12 or interferon-gamma (IFN-gamma) resulted in a dose dependent suppression of MLR in mice
Tian et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2008 (Leukemia, Promyelocytic, Acute) : The results indicated that in experiment groups, the cells had dendritic appearance and cytogenetic characteristics of APL ; expression of CD1a, CD83, CD80, CD86, HLA-DR and CD1d as well as level of IL-12 obviously increased ; the MLR and CTL effects were significant, but increase of CD1a expression in HL60-DCs did not show statistical difference from control and blank control groups