Gene interactions and pathways from curated databases and text-mining

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SLC17A5 — TNF

Text-mined interactions from Literome

Arumugam et al., Kidney Int 2003 (Disease Models, Animal...) : I/R injury was characterized by significant tissue hemorrhage with increased microvascular permeability, elevated renal tissue levels of tumor necrosis factor-alpha (TNF-alpha) and myeloperoxidase (MPO), increased serum levels of creatinine and aspartate aminotransferase (AST) and hematuria
Ohgami et al., Invest Ophthalmol Vis Sci 2003 (Uveitis, Anterior) : In addition, the effect of AST on endotoxin induced nitric oxide ( NO ), prostaglandin E2 ( PGE2 ), and tumor necrosis factor (TNF)-alpha production in a mouse macrophage cell line ( RAW 264.7 ) was studied in vitro
Romanque et al., Transplant Proc 2010 (Inflammation...) : Serum AST , ALT, and LDH levels were significantly increased by IR ( 4-, 5.6-, and 7.0-fold, respectively ), with significant changes in liver histology, protein carbonyl/GSH ratio ( 481 % enhancement ), and serum TNF-alpha ( 6.1-fold increase )
Ding et al., Hum Exp Toxicol 2012 : On day 21, the uric acid ( UA ) content of group IV was increased in serum ( p < 0.05 ) ; on day 42, the serum aspartate aminotransferase (AST) activity and the level of tumor necrosis factor (TNF)-a and interleukin (IL)-8 increased in group IV ( p < 0.05 ) ; 100 mg/kg MEL alone increased the level of TNF-a and the rate of renal apoptosis ( p < 0.05 ) ; and 33.3 mg/kg CYA alone increased the level of IL-8 and the rate of renal apoptosis ( p < 0.05 )