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CD274 — IL2

Text-mined interactions from Literome

Chen et al., Int Immunopharmacol 2005 : Moreover, the significant damping effect of sinomenine on B7-H1 and B7-DC signals could promote IL-2 and IFN-gamma production by co-cultured CD4 ( + ) T cell
Chen et al., Mol Immunol 2006 : Interestingly, the significant damping effect of triptolide on B7-H1 signal could promote interleukin-2 production by T cell hybridoma ( C10 ) after antigen presentation and enhance cytokine ( IFN-gamma and IL-2 ) secretion by anti-CD3 activated T cells
Das et al., J Immunol 2006 : Using blocking Abs to B7-H1 revealed that B7-H1 was involved in the suppression of T cell proliferation and IL-2 synthesis, and thus suggested a role for B7-H1 on the epithelium as a contributor in the chronicity of H. pylori infection
Jeong et al., J Leukoc Biol 2008 (Hepatitis C, Chronic) : Furthermore, blocking of monocyte associated B7-H1 ( moB7-H1 ) significantly enhanced the frequency of IFN-gamma producing, HCV-specific CD4+ and CD8+ effector T cells and the production of Th1 cytokines, such as IL-2 but not Th2 cytokines, including IL-4 and IL-10
Yang et al., Invest Ophthalmol Vis Sci 2008 (Melanoma...) : Expression of PD-L1 by uveal melanoma cells regulates T-cell function by suppressing IL-2 production
Nagamatsu et al., Hum Reprod 2009 : B7-H1 blockade on DSCs strongly enhanced T cell cytokine production ( IFN-gamma, TNF-alpha and IL-2 ), whereas B7-DC blockade had similar but more modest effects
Schurich et al., J Immunol 2010 : B7-H1 signals from LSECs and TCR avidity reciprocally controlled early T cell release of IL-2 and CTL differentiation
Telcian et al., J Infect Dis 2011 : Blocking PD-L1 on RSV infected BECs co-cultured with CD8 ( + ) T cells enhanced CD8 ( + ) T cell IFN-?, IL-2 , and granzyme B production
Tamura et al., Leukemia 2013 (Multiple Myeloma...) : Among major cytokines produced by HS-5 cells, interleukin (IL)-6 induced B7-H1 expression on HMCLs