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ING4 — TP53
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Bind Interaction:
TP53
—
ING4
Shiseki et al., Cancer Res 2003*
-
IRef Bind_translation Interaction:
TP53
—
ING4
(coimmunoprecipitation)
Shiseki et al., Cancer Res 2003*
-
IRef Biogrid Interaction:
ING4
—
TP53
(association, x-ray crystallography)
Palacios et al., J Mol Biol 2010
-
IRef Biogrid Interaction:
ING4
—
TP53
(physical association, affinity chromatography technology)
Shiseki et al., Cancer Res 2003*
-
IRef Biogrid Interaction:
ING4
—
TP53
(physical association, affinity chromatography technology)
Guo et al., J Biol Chem 2011*
-
IRef Biogrid Interaction:
ING4
—
TP53
(physical association, affinity chromatography technology)
Tsai et al., Exp Cell Res 2008*
-
IRef Biogrid Interaction:
ING4
—
TP53
(physical association, affinity chromatography technology)
Iizuka et al., Mol Cell Biol 2008*
-
IRef Biogrid Interaction:
ING4
—
TP53
(physical association, affinity chromatography technology)
Zhang et al., Biochem Biophys Res Commun 2005*
-
IRef Biogrid Interaction:
ING4
—
TP53
(direct interaction, pull down)
Zhang et al., Biochem Biophys Res Commun 2005*
-
IRef Hprd Interaction:
TP53
—
ING4
(in vivo)
Shiseki et al., Cancer Res 2003*
-
IRef Intact Interaction:
ING4
—
TP53
(physical association, coimmunoprecipitation)
Zhang et al., FEBS Lett 2004*
-
IRef Ophid Interaction:
ING4
—
TP53
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Shiseki et al., Cancer Res 2003
(Colorectal Neoplasms) :
p29ING4 and p28ING5 bind to p53 and p300, and
enhance p53 activity
Liu et al., J Neurooncol 2007
(Brain Neoplasms...) :
Curcumin induces G2/M cell cycle arrest in a
p53 dependent manner and upregulates
ING4 expression in human glioma
Iizuka et al., Mol Cell Biol 2008
:
Two physiological stresses that stabilize p53, hyperosmotic shock and DNA replication fork arrest, also inhibit
Hbo1 HAT activity in a
p53 dependent manner
Saha et al., J Virol 2011
(Epstein-Barr Virus Infections) :
A colony formation assay as well as an apoptosis assay showed that EBNA3C nullified the negative regulatory effects on cell proliferation induced by coupled expression of
p53 in the
presence of either
ING4 or ING5 in Saos-2 ( p53 ( -/- ) ) cells