Gene interactions and pathways from curated databases and text-mining

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ING4 — TP53

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Shiseki et al., Cancer Res 2003 (Colorectal Neoplasms) : p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity
Liu et al., J Neurooncol 2007 (Brain Neoplasms...) : Curcumin induces G2/M cell cycle arrest in a p53 dependent manner and upregulates ING4 expression in human glioma
Iizuka et al., Mol Cell Biol 2008 : Two physiological stresses that stabilize p53, hyperosmotic shock and DNA replication fork arrest, also inhibit Hbo1 HAT activity in a p53 dependent manner
Saha et al., J Virol 2011 (Epstein-Barr Virus Infections) : A colony formation assay as well as an apoptosis assay showed that EBNA3C nullified the negative regulatory effects on cell proliferation induced by coupled expression of p53 in the presence of either ING4 or ING5 in Saos-2 ( p53 ( -/- ) ) cells