Gene interactions and pathways from curated databases and text-mining

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MMP14 — NOX5

Text-mined interactions from Literome

Cook-Mills et al., Cell Mol Biol Incl Cyto Enzymol 2006 : The endothelial cell NADPH oxidase and endothelial cell MMP activities are required for VCAM-1 dependent lymphocyte migration as determined by scavenging of ROS, by pharmacologic or antisense inhibition of NADPH oxidase and by pharmacologic inhibition of endothelial cell MMPs
Kamioka et al., J Cell Physiol 2011 (Atherosclerosis) : AGE induced geranylgeranyl transferase I ( GGTase I ) activity, Rac1·p47(phox) activation, NADPH oxidase activity, ROS generation, and molecular expression were also markedly attenuated by silencing of MT1-MMP
Ando et al., J Atheroscler Thromb 2011 : The present study shows that MT1-MMP mediates the RhoA/Ca ( 2+ ) and Rac1/NADPH oxidase dependent signaling pathways in thrombin induced vascular responses