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IFNG — MICE
Text-mined interactions from Literome
Aguilar-Delfin et al., Infect Immun 2003
(Acute Disease...) :
Mice genetically deficient in
IFN-gamma mediated responses ( IFNGR2KO mice ) and IL-12 mediated responses ( Stat4KO mice ) were infected with the WA1 Babesia, and observations were made on the course of infection and cytokine responses
Lalli et al., J Parasitol 2004
(Scabies) :
Mice that were first immunized and then infested with mites
increased production of
IFNgamma by both spleen and lymph node cells
Xu et al., Proc Natl Acad Sci U S A 2008
(Arthritis, Rheumatoid) :
Mice lacking ST2, the IL-33 receptor alpha-chain, developed attenuated collagen induced arthritis ( CIA ) and
reduced ex vivo collagen-specific induction of proinflammatory cytokines ( IL-17, TNFalpha, and
IFNgamma ), and antibody production
Cong et al., Vaccine 2009
(Tularemia) :
Mice immunized with KKF235 intranasally or orally
induced robust antigen-specific splenic
IFN-gamma recall responses, as well as the production of systemic and mucosal antibodies
Logue et al., Antiviral Res 2010
(Disease Models, Animal...) :
Mice treated with CLDC had significantly
increased serum
IFN-gamma , TNF-alpha, and IL-12, suggesting a strong Th1 biased antiviral activation of the innate immune system
Matsumoto et al., J Exp Med 1998
(Malaria) :
Mice that produced low amounts of MSP1-15
stimulated IFN-gamma and could not control parasite infection