Gene interactions and pathways from curated databases and text-mining

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IFNG — MICE

Text-mined interactions from Literome

Aguilar-Delfin et al., Infect Immun 2003 (Acute Disease...) : Mice genetically deficient in IFN-gamma mediated responses ( IFNGR2KO mice ) and IL-12 mediated responses ( Stat4KO mice ) were infected with the WA1 Babesia, and observations were made on the course of infection and cytokine responses
Lalli et al., J Parasitol 2004 (Scabies) : Mice that were first immunized and then infested with mites increased production of IFNgamma by both spleen and lymph node cells
Xu et al., Proc Natl Acad Sci U S A 2008 (Arthritis, Rheumatoid) : Mice lacking ST2, the IL-33 receptor alpha-chain, developed attenuated collagen induced arthritis ( CIA ) and reduced ex vivo collagen-specific induction of proinflammatory cytokines ( IL-17, TNFalpha, and IFNgamma ), and antibody production
Cong et al., Vaccine 2009 (Tularemia) : Mice immunized with KKF235 intranasally or orally induced robust antigen-specific splenic IFN-gamma recall responses, as well as the production of systemic and mucosal antibodies
Logue et al., Antiviral Res 2010 (Disease Models, Animal...) : Mice treated with CLDC had significantly increased serum IFN-gamma , TNF-alpha, and IL-12, suggesting a strong Th1 biased antiviral activation of the innate immune system
Matsumoto et al., J Exp Med 1998 (Malaria) : Mice that produced low amounts of MSP1-15 stimulated IFN-gamma and could not control parasite infection