Gene interactions and pathways from curated databases and text-mining

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CCND1 — CDH1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Ferreira-Cornwell et al., J Cell Sci 2002 (Cardiomyopathies...) : Furthermore, E-cadherin induced cyclin D1 , nuclear reduplication, and karyokinesis in the absence of cytokinesis, resulting in myocytes with two closely opposed nuclei
Fournier et al., J Cell Sci 2008 : E-cadherin mediated cell-cell adhesion also supports cyclin D1 induction in these cells, and the combined inhibition of both E-cadherin and integrin adhesion is required to prevent the expression of cyclin D1 mRNA and protein ... Our previous studies described a pro-proliferative effect of E-cadherin in MCF10A cells, mediated by Rac, and we now show that Rac is required for cyclin D1 mRNA induction by both E-cadherin and integrin engagement
Kisslov et al., Biochim Biophys Acta 2012 (Colonic Neoplasms) : AS or Ly294002, but not H-89, decreased PKB/Akt activation as well as the nuclear localization of ß-catenin and cyclin D1 and increased the plasma membrane localization of ß-catenin with E-cadherin , suggesting that these processes are regulated by the PKB pathway ... AS or Ly294002, but not H-89, decreased PKB/Akt activation as well as the nuclear localization of ß-catenin and cyclin D1 and increased the plasma membrane localization of ß-catenin with E-cadherin , suggesting that these processes are regulated by the PKB pathway