Gene interactions and pathways from curated databases and text-mining

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BTK — CXCL12

Text-mined interactions from Literome

de Gorter et al., Immunity 2007 : Furthermore, SDF-1 induced tyrosine phosphorylation of Phospholipase Cgamma2 ( PLCgamma2 ), which, unlike activation of the migration regulatory GTPases Rac or Rap1, was mediated by Btk
Bam et al., Am J Hematol 2013 (Bone Diseases...) : SDF-1 induced BTK activation in myeloma cells and BTK inhibition by small hairpin RNA or the small molecule inhibitor, LFM-A13, reduced their migration toward stromal cell derived factor-1 (SDF-1)