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IL1R2 — RELA

Pathways - manually collected, often from reviews:

• KEGG Amoebiasis: IL1R1/IL1R2 → NFKB1/RELA (protein-protein, activation)

Text-mined interactions from Literome

Schwenzer et al., J Biol Chem 1999 : Because it has been shown that members of the TRAF family are involved in activation of NF-kappaB and the c-Jun N-terminal kinase (JNK) by the interleukin-1 receptor and members of the TNF receptor superfamily, a role of TRAF1 in receptor cross-talk and/or feedback regulation of activated receptor signaling complexes can be suggested
Loiarro et al., J Biol Chem 2009 : Moreover, overexpression of a green fluorescent protein ( GFP ) -tagged mini-MyD88 protein ( GFP-MyD88- ( 27-72 ) ), comprising the Glu ( 52 ) and Tyr ( 58 ) residues, interfered with recruitment of both IRAK1 and IRAK4 by MyD88 and suppressed NF-kappaB activation by the interleukin-1 receptor but not by the MyD88 independent TLR3