Gene interactions and pathways from curated databases and text-mining

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CDK5 — TNF

Text-mined interactions from Literome

Gaiotti et al., Mol Carcinog 2000 : Tumor necrosis factor-alpha promotes human papillomavirus ( HPV ) E6/E7 RNA expression and cyclin dependent kinase activity in HPV immortalized keratinocytes by a ras dependent pathway
Utreras et al., J Biol Chem 2009 (Pain) : Tumor necrosis factor-alpha regulates cyclin dependent kinase 5 activity during pain signaling through transcriptional activation of p35 ... These findings suggest that TNF-alpha mediated regulation of Cdk5 activity plays an important role in inflammation induced pain signaling