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ABCB1 — TNF

Text-mined interactions from Literome

Ros et al., Hepatology 2001 (Carcinoma, Hepatocellular...) : Induction of Mdr1b expression by tumor necrosis factor-alpha in rat liver cells is independent of p53 but requires NF-kappaB signaling ... We hypothesize that up-regulation of Mdr1b in these models is TNF-alpha dependent ... We aimed to elucidate the mechanism of up-regulation of Mdr1b by TNF-alpha ... In conclusion our results show that activation of the rat Mdr1b gene by TNF-alpha is a result of NF-kappaB signaling and independent of p53
Wang et al., Zhonghua Wai Ke Za Zhi 2007 (Carcinoma, Hepatocellular...) : TNF-alpha could induce down-regulation of MDR1 and up-regulation of PPAR-alpha