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CD34 — IL3

Text-mined interactions from Literome

Drouet et al., Stem Cells 2001 : We showed in a nonhuman primate model of autologous peripheral blood stem and progenitor cell transplantation that cell cycle activation of CD34 ( + ) cells in the presence of stem cell factor + FLT3-ligand + thrombopoietin + interleukin 3 ( six days of culture ) which induced G1 and S/G2/M cell amplification ( G0 : 6.1 % +/- 2.8 % ; G0/G1 : 64.2 % +/- 7.2 % ; S/G2/M : 30.4 % +/- 7.3 % respectively of expanded CD34 ( + ) cells on average ) resulted in the acceleration of short-term granulocyte recovery
Ema et al., Blood 1990 : Both CD34+ , CD33+ cells and CD34+, CD33- cells formed granulocyte/macrophage colonies in the presence of IL-3 ... Eosinophil ( Eo ) colonies were only formed by CD34+ , CD33- cells in response to IL-3 , but scarcely formed by CD34+ cells in the presence of IL-5
Strauss et al., Exp Hematol 1991 : CD34+ cells were stimulated by interleukin 3 (IL-3) over a wide concentration range : two times control at 0.1/ml, three times control at 1 ng/ml, and four times control at 10 ng/ml. Overlap between responding populations was analyzed
Panterne et al., J Cell Physiol 1993 : We further demonstrated that when a high dose of CSF-1 ( 20 ng/ml ) was added at day 7 to IL3 stimulated CD34+ cells, a rapid down-regulation of c-fms mRNA and protein was seen
Sasaki et al., Int J Hematol 1997 (Leukemia, Myeloid, Acute) : GM-CSF- and IL-3 dependent CD34 expressing myeloid cell line ( SAS-1 ) established from CD7 and CD34 expressing acute myeloblastic leukemic cells