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HIF1A — PPARG
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Belanger et al., J Mol Cell Cardiol 2002
(Anoxia) :
In contrast, neither hypoxia nor overexpression of
HIF-1alpha affected the mRNA levels of PPARalpha,
PPAR gamma , and muscle carnitine palmitoyltransferase, a known PPARalpha target gene
Krishnan et al., Cell Metab 2009
(Cardiomegaly) :
In response to pathologic stress,
HIF1alpha activates glycolytic genes and
PPARgamma , whose product, in turn, activates fatty acid uptake and glycerolipid biosynthesis genes
Zhou et al., Int J Biochem Cell Biol 2009
(Breast Neoplasms) :
HIF1 alpha and BNIP3 were among 42 genes
up-regulated by active
PPAR gamma ... Activation of
PPAR gamma induced
HIF1 alpha and BNIP3 protein and mRNA abundance