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CASP3 — IGF2

Text-mined interactions from Literome

Kondo et al., Cell Death Differ 2002 : Moreover, IGF-1 inhibited C2-ceramide induced decrease of mitochondrial membrane potential, and increase of cytochrome c release, caspase-3 cleavage and caspase-3 activity as judged by PhiPhiLux cleaving method
Ness et al., Glia 2004 : Moreover, IGF-I prevented caspase-3 activation in pro-OLs as long as 8 h after exposure of the cells to glutamate, suggesting that delayed activation of IGF-I mediated survival pathways can block glutamate mediated apoptosis in pro-OLs
Leinninger et al., Cell Death Differ 2004 (Neuroblastoma) : These results suggest that elevated glucose produces early initiator caspase activation, followed by Delta Psi ( M ) changes, in neuroblastoma cells ; in turn, IGF-I prevents apoptosis by preventing downstream caspase activation, maintaining Delta Psi ( M ) and regulating Bcl proteins
Kwon et al., Life Sci 2006 (Stomach Neoplasms) : Thus, porphyran appears to negatively regulate IGF-IR phosphorylation by causing a decrease in the expression levels in AGS gastric cancer cells, and then inducing caspase-3 activation
Yang et al., BMC cancer 2009 (Colorectal Neoplasms) : Using three colorectal cancer cell lines and one muscle cell line, associations between IGF-I and activities of caspase 3/7, 8 and 9 have been examined ; the role of insulin-like growth factor I receptor ( IGF-IR ) in the caspase activation has been investigated