Gene interactions and pathways from curated databases and text-mining

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CASP8 — PXN

Text-mined interactions from Literome

Hallé et al., Mol Cell Biol 2007 : Moreover, caspase-3 regulated PTP-PEST interactions with paxillin , leupaxin, Shc, and PSTPIP
Sohn et al., Toxicon 2008 : This disassembly of focal adhesion in saxatilin treated HCASMCs involved caspase induced paxillin degradation
Mehta et al., Am J Physiol 1998 : In the absence of extracellular Ca2+, 10 ( -4 ) M ACh induced a maximal increase in paxillin phosphorylation without increasing MLC phosphorylation or force