Gene interactions and pathways from curated databases and text-mining

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FOXO3 — PDGFB

Text-mined interactions from Literome

Yellaturu et al., J Biol Chem 2002 : In addition, NEM blocked PDGF-BB induced phosphorylation of BAD and forkhead transcription factor FKHR-L1 , and these events correlated with increased apoptosis
Abid et al., J Biol Chem 2005 (Hyperplasia) : PDGF-BB , tumor necrosis factor-alpha, and insulin-like growth factor 1 treatment resulted in the nuclear exclusion of FoxO , whereas PDGF-BB alone down-regulated the FoxO target gene, p27 ( kip1 ), and enhanced cell survival and progression through the cell cycle