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MYLIP — NFIA
Text-mined interactions from Literome
Rosa et al., Proc Natl Acad Sci U S A 2007
:
We show that PU.1 and these two components are interlinked in a finely tuned temporal and regulatory circuitry : PU.1 activates the transcription of miR-424, and this up-regulation is involved in stimulating monocyte differentiation through
miR-424 dependent translational repression of
NFI-A
Zardo et al., Blood 2012
(Leukemia) :
Moreover, ectopic
miR-223 expression in human myeloid progenitors
causes heterochromatic repression of
NFI-A gene and channels granulopoiesis, whereas its stable knockdown produces the opposite effects