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CSF2 — IL23A
Text-mined interactions from Literome
Sonderegger et al., J Exp Med 2008
(Autoimmune Diseases...) :
We found that innate
GM-CSF was
critical for IL-6 and
IL-23 responses by dendritic cells and generation of pathological Th17 cells in vivo
van de Wetering et al., PloS one 2009
(Salmonella Infections) :
In addition,
IL-23 together with IL-18 or IL-1beta
led to the production of
GM-CSF in CD56 ( + ) cells ... Both IFN-gamma and
GM-CSF enhanced
IL-23 production by monocytes in response to TLR agonists, as well as induced IL-12 production
El-Behi et al., Nat Immunol 2011
(Encephalomyelitis, Autoimmune, Experimental) :
Here we found that
IL-23 induced production of the cytokine granulocyte-macrophage colony stimulating factor (
GM-CSF ) in T ( H ) 17 cells and that GM-CSF had an essential role in their encephalitogenicity ... IL-23 induced a positive feedback loop whereby
GM-CSF secreted by T ( H ) 17 cells
stimulated the production of
IL-23 by antigen presenting cells