◀ Back to NOS1

DLG4 — NOS1

Pathways - manually collected, often from reviews:

• BioCarta nitric oxide signaling pathway: CaM/Ca ++ complex (CAMK2B) → PSD95/NOS I complex (DLG4-NOS1) (modification, activates)
  
• BioCarta nitric oxide signaling pathway: PSD95/NOS I complex (DLG4-NOS1) → NOS I (NOS1) (modification, collaborate)
• BioCarta nitric oxide signaling pathway: PSD95/NOS I complex (DLG4-NOS1) → PSD95 (DLG4) (modification, collaborate)
• BioCarta nitric oxide signaling pathway: NOS I (NOS1) → PSD95 (DLG4) (modification, collaborate)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: NOS1 — DLG4 (direct interaction, two hybrid) Brenman et al., Cell 1996*
• IRef Biogrid Interaction: NOS1 — DLG4 (physical association, affinity chromatography technology) Jaffrey et al., Neuron 1998*
• IRef Biogrid Interaction: NOS1 — DLG4 (association, biochemical) Brenman et al., Cell 1996*
• IRef Biogrid Interaction: NOS1 — DLG4 (direct interaction, pull down) Brenman et al., Cell 1996*
• IRef Hprd Interaction: DLG4 — NOS1 (two hybrid) Christopherson et al., J Biol Chem 1999*, Brenman et al., Cell 1996*, Jaffrey et al., Neuron 1998*
• IRef Hprd Interaction: DLG4 — NOS1 (in vitro) Christopherson et al., J Biol Chem 1999*, Brenman et al., Cell 1996*, Jaffrey et al., Neuron 1998*
• IRef Hprd Interaction: DLG4 — NOS1 (in vivo) Christopherson et al., J Biol Chem 1999*, Brenman et al., Cell 1996*, Jaffrey et al., Neuron 1998*
• IRef Ophid Interaction: NOS1 — DLG4 (aggregation, confirmational text mining) Brenman et al., Cell 1996*
• IRef Ophid Interaction: NOS1 — DLG4 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Yan et al., Neurosci Lett 2004 (Brain Ischemia) : Postsynaptic density protein 95 mediates Ca2+/calmodulin dependent protein kinase II-activated serine phosphorylation of neuronal nitric oxide synthase during brain ischemia in rat hippocampus
Cao et al., J Cell Biol 2005 : Although the postsynaptic density protein PSD95 can recruit the calcium dependent neuronal NO synthase (nNOS) to the mouth of the calcium-permeable NMDA receptor, and depletion of PSD95 inhibits excitotoxicity, the possibility that selective uncoupling of nNOS from PSD95 might be neuroprotective is unexplored