Gene interactions and pathways from curated databases and text-mining

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LPA — S1PR3

Text-mined interactions from Literome

Duong et al., Biochim Biophys Acta 2004 : S1P(3) was induced during differentiation but down-regulated by lipid loading and HDL ( 3 ), whereas LPA ( 1 ) was down-regulated in differentiated macrophages
Shida et al., Cancer Res 2008 (Breast Neoplasms...) : LPA transactivated the epidermal growth factor receptor (EGFR) in these cells, and the EGFR inhibitor AG1478 attenuated the increased SphK1 and S1P(3) expression induced by LPA