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BTG2 — CCND1
Text-mined interactions from Literome
Kawakubo et al., Oncogene 2004
(Breast Neoplasms) :
Consistent with the report that
BTG2 inhibits
cyclin D1 expression, suppression of BTG2 mRNA in the mammary gland during gestation, and by estrogen and progestin, correlated with stimulation of cyclin D1
Kwon et al., Int J Oncol 2005
:
Curcumin decreases cell proliferation rates through
BTG2 mediated
cyclin D1 down-regulation in U937 cells ... Furthermore, overexpression of
BTG2 led to down-regulation of
cyclin D1 mRNA expression in U937 cells
Evangelisti et al., Cell Signal 2009
:
Using DNA microarrays, Real-Time RT-PCR and western blot, we demonstrated that nuclear DGK-zeta downregulated the expression of cyclin D1 and increased the expression of
TIS21/BTG2/PC3 , a transcriptional
regulator of
cyclin D1 with a strong anti-proliferative function
Wei et al., Tumour Biol 2012
(Lung Neoplasms) :
The overexpression of
BTG2 may
inhibit the protein expression of
cyclin D1 , MMP-1, and MMP-2 in A549 cells
Zhang et al., Tumour Biol 2013
(Breast Neoplasms) :
Additionally, the
effects of
BTG2 expression on
cyclin D1 , caspase 3, and matrix metalloproteinases 1/2 (MMP-1/-2) expression were analyzed