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IGF1R — IGFBP5

Text-mined interactions from Literome

Moralez et al., J Cell Physiol 2005 (MAP Kinase Signaling System) : This mutant was equipotent compared to native IGFBP-5 in its ability to inhibit both protein synthesis and cell migration responses to IGF-I plus TS-1 thus excluding the possibility that IGFBP-5 was inhibiting the response to TS-1 and IGF-I by inhibiting IGF-I binding to the IGF-I receptor
Kalus et al., EMBO J 1998 : Remarkably, the IGF-I receptor binding assays of IGFBP-5 showed that IGFBP-5 inhibits the binding of IGFs to the IGF-I receptor , resulting in reduction of receptor stimulation and autophosphorylation