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NOS2 — RABEPK

Text-mined interactions from Literome

Pahan et al., J Biol Chem 2001 : Induction of NO production by the expression of mouse p40 cDNA but not that of the mouse p35 cDNA suggests that the p40 but not the p35 subunit of IL-12 is involved in the expression of iNOS ... Induction of the DNA binding as well as the transcriptional activity of NF-kappaB by p40 ( 2 ) and inhibition of p40 ( 2 ) -induced expression of iNOS by SN50, a cell-permeable peptide carrying the nuclear localization sequence of p50 NF-kappaB, but not by SN50M, a nonfunctional peptide mutant, suggests that p40 ( 2 ) induces the expression of iNOS through the activation of NF-kappaB
Svensson et al., Microb Pathog 2001 : Furthermore, co-incubating S. typhimurium with Mphi resulted in interleukin (IL)-12p40 , IL-6 and tumor necrosis factor-alpha production as well as iNOS induction while IL-12p70 was not detectable