Gene interactions and pathways from curated databases and text-mining

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ETS1 — NOS2

Text-mined interactions from Literome

Takahashi et al., Mol Cell Biochem 2001 : Ets-1 is involved in transcriptional regulation of the chick inducible nitric oxide synthase gene in embryonic ventricular myocytes ... Ets-1 may be involved in the iNOS gene transcription in CEVM, presumably through interacting with the NF-kappaB
Di Nunzio et al., Am J Physiol Regul Integr Comp Physiol 2002 : In addition, both ETs increased nitric oxide synthase activity
Lee et al., Infect Immun 2005 : Our data indicate that the increased Ets/Elk and NF-kappaB promoter activities associated with M. smegmatis infected macrophages are responsible , at least in part, for the increased TNF-alpha and NOS2 production observed in these infected cells and that ERK1/2 is required for Ets/Elk activity and full TNF-alpha production
Anita et al., Cell Mol Neurobiol 2006 : 1. We further characterized the effect of endothelins ( ETs ) on receptor mediated phosphoinositide ( PI ) turnover, nitric oxide synthase (NOS) activation, and cGMP formation in whole rat adrenal medulla