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AMELX — NOS2
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Wildhirt et al., Thorac Cardiovasc Surg 1999
(Myocardial Infarction...) :
However,
AMG significantly
inhibited iNOS activity, significantly improved left-ventricular maximum + dP/dt and decreased LVEDP, whereas administration of L-arginine reduced + dP/dt and slightly increased LVEDP, compared to AMG treated animals
Armstrong et al., Scand J Gastroenterol 2000
(Colitis...) :
The aim of this study was to assess
aminoguanidine (AMG) , a selective
inhibitor of inducible
nitric oxide synthase , with regard to its effectiveness as a nitric oxide inhibitor and as a modulator of inflammation in trinitrobenzene sulfonic acid ( TNBS ) -induced colitis
Jenson et al., Eur J Immunol 2002
(Filariasis...) :
Treatment of Ag-stimulated cultures with
aminoguanidine (AMG) , an
inhibitor of inducible
nitric oxide synthase , rescued the CD4 ( + ) T cells from apoptosis and reversed the proliferative defect
Ding et al., Zhejiang Da Xue Xue Bao Yi Xue Ban 2003
(Sepsis) :
The hyporeactivity to vasoconstrictors was completely reversed by pretreatment either with
aminoguanidine (AMG) , a selective inducible
nitric oxide synthase inhibitor , or with 1H [ 1,2,4 ] oxadiazolo [ 4,3-a ] quininoxalin-1-one ( ODQ ), an inhibitor of NO-sensitive guanylyl cyclase
Parlakpinar et al., Mol Cell Biochem 2005
(Myocardial Infarction...) :
In our in vivo model, we examined the effects of
aminoguanidine (AMG) , a known
iNOS inhibitor , on percentage infarct size in anaesthetized rats
Parlakpinar et al., Int J Urol 2006
(Disease Models, Animal...) :
The aim of this study was to investigate whether NO has a role in this damage, using
aminoguanidine (AMG) , a known
iNOS inhibitor and an antioxidant, in rats undergoing MI/R
Xu et al., J Cardiovasc Pharmacol 2008
:
Rats were injected with ISO ( 1 mg/kg, SC ) for 10 days to induce vascular dysfunction and treated with CPU0213 ( 30 mg/kg, SC ) or aminoguanidine (
AMG , an
inhibitor of
iNOS , 100 mg/kg, PO ) from day 7 to day 10
Bang et al., Blood 1996
:
To further characterize these responses and determine if they are related, recipient BALB/c H-2d mice were treated with
aminoguanidine (AMG) , a selective
inhibitor of
inducible nitric oxide synthase (iNOS) , and transfused weekly with 2 x 10 ( 8 ) C57BL/6 H2b platelets
Salvucci et al., Blood 1998
:
When
aminoguanidine (AMG) , an
inhibitor of
iNOS , was added during the afferent phase of NK stimulation with IL-12 and TNFalpha, a subsequent increase in the lytic potential of the effector cells towards the NK-sensitive target cells ( K562 ) and lymphokine activated killer ( LAK ) target cells ( Daudi ) was observed