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IRF1 — SOCS1

Pathways - manually collected, often from reviews:

• NCI Pathway Database IFN-gamma pathway: IRF1 (IRF1) → SOCS1 (SOCS1) (transcription, activates) Dickensheets et al., Proc Natl Acad Sci U S A 1999*, Varinou et al., Immunity 2003, Tahk et al., Proc Natl Acad Sci U S A 2007*
  Evidence: mutant phenotype, other species

Text-mined interactions from Literome

Saito et al., J Immunol 2000 : Furthermore, forced expression of IRF-1 mimicked and that of IRF-2 inhibited the stimulatory effect of IFN-gamma on SSI-1 gene transcription
Letourneur et al., Mol Immunol 2009 : Socs1 expression is induced in the human keratinocytes HaCaT cell line through sequential activation of STAT1 and IRF-1