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HSPG2 — IL1A
Text-mined interactions from Literome
García de Yébenes et al., J Neurochem 1999
(Alzheimer Disease...) :
We thus studied
perlecan regulation by
IL-1alpha , in vivo
Amin et al., Int J Oncol 2003
:
Moreover,
IL-1beta induced association of
PLC-gamma with SHPS-1
Galella et al., Biochem Pharmacol 1992
:
These data suggest that, in monocytes,
IL-1 does not directly
stimulate a PLA2 or a
PLC active on phosphatidylinositol ; instead it primarily stimulates a PLC active on PC
Kim et al., J Immunol 2012
(Disease Models, Animal...) :
In a second model of sepsis,
PLC activation also
inhibited the production of TNF-a and
IL-1ß following systemic LPS challenge
Mochan et al., Agents Actions 1989
(Arthritis, Rheumatoid) :
On the other hand, the
IL-1 induction of collagenase may primarily
involve PLC and protein kinase C activation
Marmiroli et al., J Biol Chem 1994
(Osteosarcoma) :
Moreover, the increase of
PLC activity in
response to
IL-1 alpha is completely neutralized by monoclonal antibody against the beta-form