Gene interactions and pathways from curated databases and text-mining

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NOX1 — PDK1

Text-mined interactions from Literome

Block et al., J Biol Chem 2008 (Fibrosis...) : Nox4 NAD ( P ) H oxidase mediates Src dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II : role in mesangial cell hypertrophy and fibronectin expression
Yang et al., Eur J Pharmacol 2010 : These results suggest that plumbagin activates NAD ( P ) H oxidase , Src, and PI3K, and that the activated PI3K or PDK1 subsequently stimulate Akt and Ras-Raf-MEK1/2-ERK1/2 in 3T3-L1 cells