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GRP — IFI44

Text-mined interactions from Literome

Lui et al., Oncogene 2003 (Carcinoma, Squamous Cell...) : In HNSCC cells that express elevated levels of both GRPR and EGFR, we found that GRP induced rapid phosphorylation of EGFR as well as p44/42-MAPK activation ... Using several EGFR-specific tyrosine kinase inhibitors and cells derived from EGFR knockout mice, we demonstrated that GRP induced p44/42-MAPK activation was dependent upon EGFR activation
Zhang et al., Cancer Res 2004 (Carcinoma, Squamous Cell...) : GRP can induce rapid phosphorylation of EGFR and p42/44 mitogen activated protein kinase ( MAPK ) activation in part via extracellular release of transforming growth factor alpha ( TGF-alpha ) by matrix metalloproteinases ( MMPs )