Gene interactions and pathways from curated databases and text-mining

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LPA — NOS2

Text-mined interactions from Literome

Moeslinger et al., FEBS Lett 2000 (Arteriosclerosis) : Ox-Lp(a) induced iNOS inhibition might contribute to the development of atherosclerotic lesions by reducing the anti-atherogenic effects of nitric oxide
Gobeil et al., J Biol Chem 2003 : Moreover, LPA induced increases in Ca2+ transients and/or iNOS expression in highly purified rat liver nuclei were prevented by pertussis toxin, phosphoinositide 3-kinase/Akt inhibitor wortmannin and Ca2+ chelator and channel blockers EGTA and SK & F96365, respectively
Brault et al., Am J Physiol Regul Integr Comp Physiol 2007 : LPA decreased intracellular GSH levels and induced a p38 MAPK/JNK dependent inducible nitric oxide synthase (NOS) expression