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NGF — PRKACG
Text-mined interactions from Literome
Obara et al., J Cell Sci 2004
:
In these cells, Rap1 is required for
cAMP/PKA signaling to ERKs and also for the sustained
activation of ERKs by
NGF ... These results strongly indicate that
PKA phosphorylation of Src at S17 is
essential for cAMP and
NGF signaling in PC12 cells and identify PKA as an important downstream target of NGF
Park et al., Mol Cells 2006
:
The p38 mitogen activated protein kinase ( MAPK ) inhibitor, SB203580, phosphatidylinositol 3-kinase (PI-3K) inhibitor, LY294003,
protein kinase A (PKA) inhibitor, H89, and protein kinase C ( PKC ) inhibitor, chelerythrine,
had no effect on activation of promoter IV by
NGF
Yao et al., J Biol Chem 1998
:
The cyclic adenosine monophosphate dependent
protein kinase (PKA) is
required for the sustained activation of mitogen activated kinases and gene expression by
nerve growth factor ... Here we show that maximal sustained activation of ERK1 by
NGF requires
PKA ... Inhibitors of
PKA partially
blocked activation of ERK1 by
NGF but had no effect on activation of ERK1 by EGF