Hannila et al., Eur J Neurosci 2004
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This study examined the effects of hypomorphic p75 neurotrophin receptor (p75NTR) expression and high levels of nerve growth factor (NGF) on trkA phosphorylation and downstream activation of p44/42 mitogen activated protein kinase ( MAPK )
Moughal et al., J Neurochem 2006
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In contrast, the stimulation of PC12 cells with LPA leads to a predominant G ( i ) alpha2 mediated Trk A-independent activation of p42/p44 MAPK, where Gbetagamma subunits play a diminished role