◀ Back to TLR2

CSK — TLR2

Text-mined interactions from Literome

Yoshida et al., J Biol Chem 2005 (Inflammation) : We showed that activation of TLR2 signaling by TLR2 ligands including peptidoglycan ( PGN ), MALP-2, and Pam3CSK4 induces activation of IKKs-IkappaBalpha and MKK3/6-p38 pathways not only by TRAF6 but also by TRAF7, a recently identified TRAF family member
Tobias et al., Biochem Soc Trans 2007 (Atherosclerosis...) : In contrast, the proatherogenic TLR2 responses to the defined synthetic exogenous agonist Pam3 CSK4 are mediated at least in part by BMDC, which can include lymphocytes, monocytes/macrophages and dendritic cells
Dasu et al., Atherosclerosis 2009 (Inflammation) : Pam3CSK4 and LPS induced TLR2 and TLR4 expression at mRNA and protein levels are inhibited by candesartan both in vitro and in vivo
Liang et al., J Immunol 2009 : Moreover, the putative LT-IIb-B ( 5 ) binding site overlaps partially with that of Pam ( 3 ) CSK ( 4 ) ; consistent with this, Pam ( 3 ) CSK ( 4 ) suppressed TLR2 binding of LT-IIb-B ( 5 ), albeit not as potently as self-competitive inhibition
Langlet et al., Eur J Immunol 2010 : Finally, co-immunoprecipitation assays revealed that PKC-alpha physically interacts with Pam ( 3 ) CSK ( 4 ) activated TLR2 in WT but not in MyD88 ( -/- ) DC