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RELA — STAP2
Text-mined interactions from Literome
Sekine et al., J Immunol 2006
:
Disruption of
STAP-2 resulted in impaired LPS/TLR4 induced cytokine production and
NF-kappaB activation
Ikeda et al., Mol Cell Biol 2008
:
STAP-2 negatively
regulates both canonical and noncanonical
NF-kappaB activation induced by Epstein-Barr virus derived latent membrane protein 1 ... In the present study, we found that ectopic expression of
STAP-2 inhibited Epstein-Barr virus ( EBV ) LMP1 mediated
NF-kappaB signaling and interleukin-6 expression ... We found, furthermore, that
STAP-2 regulated LMP1 mediated
NF-kappaB signaling through direct or indirect interactions with the tumor necrosis factor receptor (TNFR) associated factor 3 ( TRAF3 ) and TNFR associated death domain (TRADD) proteins