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AKT2 — CSE
Text-mined interactions from Literome
Michaud et al., J Mol Cell Cardiol 2006
(Cardiovascular Diseases) :
We found that
CSE inhibited
Akt/eNOS phosphorylation and NO release in VEGF stimulated HUVECs
Kim et al., Exp Mol Med 2009
:
In isolated rat AMs,
CSE induced MMP-9 expression and phosphorylation of ERK and
Akt ... A chemical inhibitor of MEK1/2 or PI3K reduced phosphorylation of ERK or
Akt , respectively, and also
inhibited CSE mediated MMP-9 induction ... Simvastatin attenuated
CSE mediated activation of RAS and phosphorylation of ERK,
Akt , p65, IkappaB, and nuclear AP-1 or NF-kappaB activity
Mortaz et al., Respir Res 2009
:
Moreover,
CSE suppressed
PI3K/Akt signalling in pDC
Kim et al., J Biol Chem 2011
(Pulmonary Emphysema) :
TTC3 siRNAs suppressed not only
CSE induced
Akt degradation but also CSE induced cytotoxicity