Gene interactions and pathways from curated databases and text-mining

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AKT2 — CSE

Text-mined interactions from Literome

Michaud et al., J Mol Cell Cardiol 2006 (Cardiovascular Diseases) : We found that CSE inhibited Akt/eNOS phosphorylation and NO release in VEGF stimulated HUVECs
Kim et al., Exp Mol Med 2009 : In isolated rat AMs, CSE induced MMP-9 expression and phosphorylation of ERK and Akt ... A chemical inhibitor of MEK1/2 or PI3K reduced phosphorylation of ERK or Akt , respectively, and also inhibited CSE mediated MMP-9 induction ... Simvastatin attenuated CSE mediated activation of RAS and phosphorylation of ERK, Akt , p65, IkappaB, and nuclear AP-1 or NF-kappaB activity
Mortaz et al., Respir Res 2009 : Moreover, CSE suppressed PI3K/Akt signalling in pDC
Kim et al., J Biol Chem 2011 (Pulmonary Emphysema) : TTC3 siRNAs suppressed not only CSE induced Akt degradation but also CSE induced cytotoxicity