◀ Back to RAC1

RAC1 — SLC9A1

Text-mined interactions from Literome

Paradiso et al., Breast Cancer Res 2004 (Breast Neoplasms...) : The regulation of NHE1 activity by RhoA and Rac1 in both conditions was mediated by an alteration in intracellular proton affinity of the exchanger ... Interestingly, the role of each of these G-proteins was reversed during serum deprivation ; basal NHE1 activity was regulated positively by RhoA and negatively by Rac1, whereas RhoA negatively and Rac1 positively directed the stimulation of NHE1 during serum deprivation
Hooley et al., J Biol Chem 1996 : Constitutively active Rac1V12 does stimulate NHE1 through a MEKK1 dependent mechanism, but dominant interfering Rac1N17 does not inhibit Galpha 13QL mediated or constitutively active Cdc42V12 mediated stimulation of the exchanger ... Conversely, Cdc42NI7 does not inhibit Rac1V12 activation of NHE1 , suggesting that Rae I and Cdc42 independently regulate a MEKK1 dependent activation of the exchanger