Gene interactions and pathways from curated databases and text-mining

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SPP1 — WNT1

Text-mined interactions from Literome

Rohde et al., Int J Cancer 2007 (Adenoma...) : The in vivo role of Wnt signaling for the expression of OPN was tested in genetically defined mouse models with ( Apc ( 1638N ) ) or without ( pvillin-KRAS ( V12G ) ) Wnt activating mutations
Scheller et al., J Dent Res 2008 : Northern blot analysis found that Wnt-1 strongly induced the expression of matricellular protein osteopontin , and modestly enhanced the expression of type I collagen in DPSCs. Unexpectedly, Wnt-1 inhibited alkaline phosphatase (ALP) activity and the formation of mineralized nodules in DPSCs
Ravindranath et al., Br J Cancer 2011 (Breast Neoplasms...) : Wnt-ß-catenin-Tcf-4 signalling modulated invasiveness is dependent on osteopontin expression in breast cancer ... Osteopontin was activated by Wnt signalling in MDA MB 231 cells