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ITGB1 — PRKAR1B

Pathways - manually collected, often from reviews:

• BioCarta mcalpain and friends in cell motility: Paxillin/FAK/Talin/MLC(+)/Integrin-alpha/Integrin-beta/ECM complex (PXN-PTK2-TLN1-MLC1-ITGA1-ITGB1) → PKA complex (PRKACB-PRKACG-PRKAR1A-PRKAR1B-PRKAR2A-PRKAR2B) (modification, collaborate)
  
• NCI Pathway Database Alpha4 beta1 integrin signaling events: Type I PKA complex (PRKACA-PRKAR1A-PRKAR1B-PRKACB) → alpha4/beta1 Integrin/Fibronectin complex (ITGA4-ITGB1-FN1) (modification, activates)
  Liu et al., Nature 1999, Han et al., J Biol Chem 2001, Han et al., J Biol Chem 2003, Nishiya et al., Nat Cell Biol 2005
  Evidence: assay, physical interaction
• NCI Pathway Database Alpha4 beta1 integrin signaling events: Type I PKA complex (PRKACA-PRKAR1A-PRKAR1B-PRKACB) → alpha4/beta1 Integrin/Fibronectin/Paxillin complex (PXN-ITGA4-ITGB1-FN1) (modification, activates)
  Liu et al., Nature 1999, Han et al., J Biol Chem 2001, Han et al., J Biol Chem 2003, Nishiya et al., Nat Cell Biol 2005
  Evidence: assay, physical interaction