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CAV3 — EMP2

Text-mined interactions from Literome

Wadehra et al., Mol Biol Cell 2004 : These findings suggest that EMP2 facilitates the formation and surface trafficking of lipid rafts bearing GPI-APs, and reduces caveolin expression, resulting in impaired formation of caveolae
Forbes et al., J Biol Chem 2007 : The tetraspan protein EMP2 regulates expression of caveolin-1 ... In this study, we analyzed the mechanism of EMP2 mediated caveolin-1 regulation ... In NIH 3T3 cells and in the human retinal pigment epithelium cell line ( ARPE-19 ), EMP2 regulates caveolin-1 transcription and more substantially its protein levels ... EMP2 mediated down-regulation of caveolin-1 does not affect caveolin-1 translational efficiency, phosphorylation, or proteasome mediated degradation ... Analysis of caveolin-1 protein half-life indicates the EMP2 mediated loss of caveolin-1 occurs rapidly