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IL21 — TCF12
Text-mined interactions from Literome
McDermott et al., Trends Mol Med 2002
(Familial Mediterranean Fever...) :
Disorders of
interleukin-1 processing and of
regulation of nuclear factor kappaB
transcription factor , and possibly defective apoptosis, might be involved in the pathogenesis of all but one of these disorders
Wei et al., J Biol Chem 2007
:
IL-21 also
induces IL-17 production and expression of the
transcription factor , RORgammat
Chen et al., Immunol Res 2008
(Bacterial Infections) :
In the mouse, the differentiation of this new lineage is initiated by TGFbeta-1 and IL-6 and
IL-21 , which activate Stat3 and
induce the expression of the
transcription factor retinoic acid related orphan receptor ( RORgammat )
Sheikh et al., Hepatology 2008
(Hepatitis C...) :
This
transcription factor plays a key role in the expression of cytokines, tumor necrosis factor alpha (TNF-alpha),
interleukin 6, interleukin 8, tumor growth factor beta, and Fas ligand
Chen et al., Immunity 2008
(Arthritis, Rheumatoid...) :
IRF-4 binding protein
inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4
transcription factor ... IRF-4 binding protein
inhibits interleukin-17 and
interleukin-21 production by controlling the activity of IRF-4
transcription factor
Saraiva et al., Immunity 2009
:
Interleukin-10 production by Th1 cells requires
interleukin-12 induced STAT4
transcription factor and ERK MAP kinase activation by high antigen dose
Chen et al., J Immunol 2010
(Encephalomyelitis, Autoimmune, Experimental) :
Regulation of the
IL-21 gene by the NF-?B
transcription factor c-Rel
Sung et al., J Biol Chem 1993
:
Stimulation of
interleukin-1 gene transcription may be
caused by the stimulation of
transcription factor activities, including those of AP-1, by these protein phosphatase inhibitors