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EPHB2 — PTPRJ
Text-mined interactions from Literome
Massa et al., J Biol Chem 2004
(Glioma) :
Somatostatin treatment increased the activity of
DEP-1/PTPeta and
inhibited ERK1/2 activation
Brunner et al., Blood 2011
(MAP Kinase Signaling System) :
Consistently, the receptor-like protein tyrosine phosphatase
DEP-1 ( density enhanced phosphatase-1/CD148 ), which is abundantly expressed in confluent endothelial cells,
inhibited the VEGF dependent activation of
ERK1/2 , leading to down-regulation of uPAR expression