Gene interactions and pathways from curated databases and text-mining

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EPHB2 — PTPRJ

Text-mined interactions from Literome

Massa et al., J Biol Chem 2004 (Glioma) : Somatostatin treatment increased the activity of DEP-1/PTPeta and inhibited ERK1/2 activation
Brunner et al., Blood 2011 (MAP Kinase Signaling System) : Consistently, the receptor-like protein tyrosine phosphatase DEP-1 ( density enhanced phosphatase-1/CD148 ), which is abundantly expressed in confluent endothelial cells, inhibited the VEGF dependent activation of ERK1/2 , leading to down-regulation of uPAR expression